Endocrinology Quiz #17: Acromegaly

1. A 45-year-old man presents with complaints of increasing shoe size, ring tightness, and coarse facial features over the past five years. He also reports sleep apnea and joint pain. Laboratory tests reveal elevated levels of insulin-like growth factor 1 (IGF-1). MRI of the brain shows a pituitary adenoma. Which of the following hormones is most directly responsible for the patient's symptoms?

Question 1 of 5

2. A 50-year-old woman undergoes surgery for a pituitary adenoma due to acromegaly. Postoperatively, she develops diabetes insipidus. Which of the following best explains the pathophysiology of her new condition?

Question 2 of 5

3. A patient with acromegaly is found to have elevated levels of serum growth hormone. Which of the following tests is most useful in confirming the diagnosis of acromegaly? 

Question 3 of 5

4. A 38-year-old man with acromegaly undergoes successful transsphenoidal surgery to remove a pituitary adenoma. Which of the following outcomes is most likely to improve following surgery? 

Question 4 of 5

5. A patient with acromegaly is noted to have enlargement of the internal organs, including the heart. This patient is at increased risk for which of the following complications?

Question 5 of 5


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