Endocrinology Quiz #24: Hyperaldosteronism

1. A 50-year-old woman presents with progressively worsening muscle weakness and hypertension. Laboratory tests reveal hypokalemia and metabolic alkalosis. Plasma renin activity is low, and aldosterone levels are significantly elevated. Which of the following is the most likely diagnosis? 

Question 1 of 5

2. A 60-year-old man with a history of diabetes and chronic kidney disease presents with hyperkalemia and mild renal insufficiency. His medications include an ACE inhibitor. Plasma aldosterone levels are low, and plasma renin activity is decreased. Which of the following conditions is most consistent with these findings? 

Question 2 of 5

3. A 45-year-old female presents with hypertension, headache, and episodes of muscle weakness. Laboratory tests reveal hypokalemia. Further evaluation shows elevated aldosterone levels with suppressed plasma renin activity. A CT scan of the abdomen reveals a small mass in the left adrenal gland. Which of the following treatments is most appropriate for this condition? 

Question 3 of 5

4. A 37-year-old man presents to the clinic with fatigue, muscle cramps, and a recent history of salt craving. Laboratory tests show hyperkalemia, mild metabolic acidosis, and normal renal function. Plasma renin activity is elevated, but aldosterone levels are inappropriately low for the level of renin. Which of the following is the most likely diagnosis? 

Question 4 of 5

5. A patient with longstanding hypertension is diagnosed with primary hyperaldosteronism and is started on spironolactone therapy. After starting treatment, the patient reports improvement in blood pressure control and resolution of previous symptoms. The mechanism of action of spironolactone in treating this condition is best described as which of the following? 

Question 5 of 5


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