Endocrinology Quiz #26: Multiple Endocrine Neoplasia Syndromes

1. A 32-year-old man presents with recurrent episodes of sweating, headache, and palpitations. His blood pressure is found to be elevated during these episodes. He also reports a history of kidney stones and has recently been diagnosed with a thyroid nodule. Which of the following is the most likely diagnosis? 

Question 1 of 5

2. A 28-year-old woman presents with hypercalcemia and a history of recurrent peptic ulcers. She also reports that her father had similar health issues and underwent surgery for a pancreatic tumor. Which of the following genetic mutations is most likely associated with her condition? 

Question 2 of 5

3. A 45-year-old male is diagnosed with a medullary thyroid carcinoma (MTC). During the workup, he is also found to have elevated calcium levels due to parathyroid hyperplasia and a mass on his adrenal gland suggestive of a pheochromocytoma. Which of the following interventions is most appropriate to decrease his risk of developing metastatic disease? 

Question 3 of 5

4. A 30-year-old woman with a known diagnosis of Multiple Endocrine Neoplasia type 1 (MEN1) presents for follow-up. She was previously treated for primary hyperparathyroidism. Which of the following screenings is most important for early detection of a common associated condition in MEN1? 

Question 4 of 5

5. A 20-year-old male with a family history of Multiple Endocrine Neoplasia type 2 (MEN2) is found to have a RET proto-oncogene mutation on genetic testing. Which of the following prophylactic measures is most appropriate to reduce his risk of medullary thyroid carcinoma (MTC)? 

Question 5 of 5


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