Gastroenterology Quiz #17: Achalasia and Esophageal Diseases

1. A 50-year-old man presents with progressive difficulty swallowing both solids and liquids over the past 6 months. He also reports regurgitation of undigested food and occasional chest pain. Barium swallow study shows a dilated esophagus with a bird's beak appearance at the distal end. Which of the following is the most likely diagnosis? 

Question 1 of 5

2. A 45-year-old woman with a history of difficulty swallowing undergoes manometry, which shows high resting pressure in the lower esophageal sphincter (LES) and absence of peristalsis in the esophageal body. Which of the following is the most likely pathophysiological mechanism of her condition? 

Question 2 of 5

3. A patient with long-standing achalasia is at increased risk for developing which of the following conditions? 

Question 3 of 5

4. A patient presents with a history of heartburn, regurgitation, and nocturnal cough. An upper endoscopy reveals erythema and erosions in the distal esophagus. Which of the following is the most appropriate initial management for this condition? 

Question 4 of 5

5. A 60-year-old man with a history of achalasia undergoes an esophagogastroduodenoscopy (EGD), which reveals a large mass in the distal esophagus. Biopsy confirms esophageal squamous cell carcinoma. Which of the following factors is most likely to have contributed to the development of his cancer? 

Question 5 of 5


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