Gastroenterology Quiz #20: Gastric Ulcers and Cancer

1. A 55-year-old man presents with a 4-month history of epigastric pain that worsens after eating. He has lost 10 pounds in the last two months and reports no relief from over-the-counter antacids. An endoscopy reveals a 2 cm ulcer on the lesser curvature of the stomach. Biopsy of the ulcer edge shows malignant cells. Which of the following is the most common type of gastric cancer found in this patient? 

Question 1 of 5

2. A 45-year-old woman with a history of rheumatoid arthritis treated with long-term nonsteroidal anti-inflammatory drugs (NSAIDs) presents with epigastric pain that improves with eating. An endoscopy reveals an ulcer in the antrum of the stomach. Which of the following is the most likely cause of her gastric ulcer? 

Question 2 of 5

3. A 62-year-old man presents with vague epigastric discomfort, early satiety, and unintentional weight loss. An endoscopy reveals a mass in the body of the stomach, and biopsy confirms poorly differentiated adenocarcinoma. Which of the following factors is most strongly associated with the development of this type of gastric cancer?

Question 3 of 5

4. A 50-year-old man presents with a 6-month history of epigastric pain, nausea, and vomiting. He also reports a feeling of fullness after eating small amounts of food. Laboratory tests reveal microcytic anemia. An endoscopy shows a 3 cm ulcer with irregular borders on the greater curvature of the stomach. What is the most significant risk factor for the development of this patient's condition? 

Question 4 of 5

5. A 68-year-old woman presents with a 3-month history of non-specific abdominal discomfort and weight loss. She has no history of nonsteroidal anti-inflammatory drug (NSAID) use. Laboratory tests reveal iron deficiency anemia and hypoalbuminemia. Endoscopy shows a large, fungating mass in the fundus of the stomach, and biopsy confirms adenocarcinoma. Which of the following paraneoplastic syndromes is most commonly associated with this patient's type of cancer? 

Question 5 of 5


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