Gastroenterology Quiz #31: Liver Tumors and Autoimmune Hepatitis

1. A 30-year-old woman presents to the clinic with fatigue, joint pain, and pruritus. Laboratory findings show elevated serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST), with a positive antinuclear antibody (ANA) and smooth muscle antibody (SMA). There is no history of alcohol abuse or viral hepatitis. Which of the following is the most likely diagnosis? 

Question 1 of 5

2. A 45-year-old man with a history of hepatitis C and cirrhosis presents with weight loss and a palpable mass in the right upper quadrant of the abdomen. An abdominal CT scan reveals a solitary liver lesion with arterial enhancement and venous washout. Alpha-fetoprotein (AFP) levels are significantly elevated. Which of the following is the most likely diagnosis? 

Question 2 of 5

3. A 25-year-old female presents with right upper quadrant pain and is found to have a liver mass on ultrasound. Further imaging with MRI shows a well-circumscribed lesion with a central scar. The patient is otherwise healthy, with no history of liver disease. Which of the following is the most likely diagnosis? 

Question 3 of 5

4. A 50-year-old man presents with abdominal pain and jaundice. Laboratory tests reveal elevated liver enzymes, and an abdominal ultrasound shows dilated intrahepatic bile ducts and a mass at the confluence of the right and left hepatic ducts. CA 19-9 levels are elevated. Which of the following is the most likely diagnosis? 

Question 4 of 5

5. A 40-year-old woman presents with a 6-month history of malaise, anorexia, and arthralgia. Laboratory tests show elevated liver enzymes and high serum immunoglobulin G (IgG) levels. Liver biopsy reveals interface hepatitis, plasma cell infiltration, and rosette formation of hepatocytes. Which of the following is the most likely diagnosis? 

Question 5 of 5


 

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