Hem/Onc Quiz #10: Red Blood Cell Morphology and Inclusions

1. A 65-year-old man with a history of chronic obstructive pulmonary disease presents to the clinic for a routine check-up. His blood smear is shown to have an increased concentration of RBCs with a central area of pallor that occupies more than one-third of the cell diameter. This finding is most indicative of which of the following conditions?

Question 1 of 5

2. A 30-year-old woman from the Mediterranean region presents with fatigue and jaundice. Blood smear examination reveals numerous small, round, dense RBCs without the central area of pallor. Which of the following is the most likely diagnosis?

Question 2 of 5

3. A 20-year-old African American man presents to the emergency department with severe pain in his legs and back. A blood smear shows elongated and sickle-shaped red blood cells. This aberrant cell shape is most directly a consequence of which of the following?

Question 3 of 5

4. A 50-year-old man with a history of alcoholism presents with weakness and light-headedness. Laboratory findings reveal macrocytic anemia. Blood smear examination would most likely show which of the following features?

Question 4 of 5

5. A 7-year-old boy presents with pallor and lethargy. His parents report a recent episode of bloody diarrhea. Laboratory tests reveal a hemoglobin level of 7 g/dL. Blood smear shows fragmented red cells (schistocytes). Which of the following is the most likely diagnosis?

Question 5 of 5


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