Hem/Onc Quiz #12: Macrocytic Anemias

1. A 52-year-old man with a long history of alcohol abuse presents with weakness and a sore tongue. Laboratory tests reveal a hemoglobin level of 10 g/dL and a mean corpuscular volume (MCV) of 110 fL. A deficiency in which of the following is the most likely cause of this patient's anemia?

Question 1 of 5

2. A 47-year-old woman presents with fatigue, pallor, and paresthesia in her hands and feet. Laboratory findings reveal a hemoglobin of 9.8 g/dL, MCV of 115 fL, and hypersegmented neutrophils on a peripheral blood smear. Which of the following is the most likely diagnosis?

Question 2 of 5

3. A 35-year-old woman with a vegan diet presents to the clinic with complaints of fatigue and weakness. Blood tests reveal macrocytic anemia. Which of the following additional findings is most likely associated with her condition?

Question 3 of 5

4. A 60-year-old man is diagnosed with macrocytic anemia. His medical history is significant for type 2 diabetes mellitus, for which he has been taking metformin for several years. Which of the following mechanisms most likely explains the cause of his anemia?

Question 4 of 5

5. A 25-year-old female presents with fatigue and difficulty concentrating. Laboratory tests show anemia with an MCV of 104 fL. Her dietary history reveals strict adherence to a diet free of animal products. Despite her diet, which of the following laboratory findings would be most consistent with a diagnosis of folate deficiency rather than vitamin B12 deficiency?

Question 5 of 5


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