Hem/Onc Quiz #18: Platelet Disorders

1. A 28-year-old woman presents to her primary care physician with complaints of easy bruising and frequent nosebleeds. She mentions that these symptoms have been persistent for the past few months. Laboratory tests show a normal platelet count, prolonged bleeding time, and normal prothrombin time (PT) and activated partial thromboplastin time (aPTT). Which of the following is the most likely diagnosis?

Question 1 of 5

2. A 4-year-old boy is brought to the pediatrician by his parents who are concerned about the appearance of small, pinpoint red spots on his legs and arms. The child has had no recent infections or illnesses. The physical examination reveals petechiae but no significant bruising or bleeding. A complete blood count (CBC) shows a platelet count of 20,000/μL. Which of the following is the most likely diagnosis?

Question 2 of 5

3. A 65-year-old man with a history of coronary artery disease presents to the emergency department with acute onset of chest pain. He has been taking aspirin daily. Laboratory tests show a normal platelet count but prolonged bleeding time. Which of the following mechanisms is most likely responsible for his prolonged bleeding time?

Question 3 of 5

4. A 7-year-old girl is diagnosed with thrombotic thrombocytopenic purpura (TTP) after presenting with fever, neurological symptoms, renal impairment, and thrombocytopenia. Which of the following findings is characteristic of this condition?

Question 4 of 5

5. A 2-year-old boy is brought to the pediatrician by his parents who are concerned about his frequent nosebleeds and a recent episode of prolonged bleeding from a minor cut. Physical examination reveals several large bruises on his legs and arms. Laboratory tests show a platelet count of 450,000/μL, prolonged bleeding time, and normal PT and aPTT. Further testing reveals abnormal platelet aggregation in response to ristocetin. Which of the following is the most likely diagnosis? 

Question 5 of 5


 

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