Hem/Onc Quiz #19: Thrombotic Microangiopathies

1. A 28-year-old woman presents with fatigue, pallor, and petechiae. Laboratory findings reveal microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. A stool sample is negative for Shiga toxin. Which of the following is the most likely diagnosis? 

Question 1 of 5

2. A 3-year-old boy is brought to the pediatrician by his mother due to bloody diarrhea followed by the development of pallor and reduced urine output. Laboratory tests confirm microangiopathic hemolytic anemia and thrombocytopenia. A stool sample is positive for Shiga toxin. Which of the following conditions is the child most likely suffering from? 

Question 2 of 5

3. A patient presents with microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney failure. Complement levels are found to be abnormally low. Which of the following is the most appropriate initial treatment? 

Question 3 of 5

4. A 45-year-old man with a history of HIV infection presents with neurological symptoms, renal impairment, and a blood smear showing schistocytes. ADAMTS13 activity is found to be less than 5%. Which of the following is the most likely diagnosis? 

Question 4 of 5

5. A patient presents with fever, neurological changes, renal failure, thrombocytopenia, and microangiopathic hemolytic anemia. Which of the following laboratory findings is most indicative of thrombotic thrombocytopenic purpura (TTP)? 

Question 5 of 5


 

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