Hem/Onc Quiz #21: Blood Transfusions

1. A 65-year-old male with a history of chronic anemia secondary to kidney disease is scheduled to receive a blood transfusion. Shortly after initiation of the transfusion, he develops fever, chills, and back pain. Laboratory tests show an increase in bilirubin levels and a decrease in haptoglobin. Which of the following is the most likely cause of this patient's symptoms? 

Question 1 of 5

2. A 30-year-old female with a history of multiple pregnancies receives a blood transfusion for the first time due to severe anemia following surgery. She develops respiratory distress, hypoxemia, and bilateral pulmonary edema within 6 hours of the transfusion, but without evidence of circulatory overload. Which of the following is the most likely diagnosis? 

Question 2 of 5

3. A patient receives a red blood cell transfusion for severe anemia and develops urticaria and pruritus shortly after the transfusion starts, but no respiratory or cardiovascular symptoms. Which of the following is the most appropriate next step in management?

Question 3 of 5

4. A 50-year-old male with a history of chronic transfusion therapy for thalassemia develops new-onset diabetes and abnormal liver function tests. Serum ferritin is significantly elevated. Which of the following complications is most likely responsible for these findings?

Question 4 of 5

5. A 22-year-old female with no significant medical history develops fever, chills, and a headache 10 days after receiving a transfusion for blood loss during surgery. Laboratory tests show a decrease in hemoglobin and an increase in lactate dehydrogenase (LDH). Direct Coombs test is positive. Which of the following is the most likely diagnosis? 

Question 5 of 5


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