Immunology Quiz #13: Cytokines

1. A 25-year-old male presents with fever, chills, and muscle aches shortly after beginning treatment for chronic hepatitis C infection with a new medication. The patient's symptoms are most likely mediated by the action of which of the following cytokines that is commonly used in the treatment of hepatitis C and has antiviral properties? 

Question 1 of 5

2. A 30-year-old woman with a history of autoimmune thyroiditis presents to her physician with new-onset joint pain and stiffness. Laboratory tests reveal elevated levels of a cytokine known to play a key role in both innate and adaptive immune responses, often associated with autoimmune and inflammatory disorders. Which of the following cytokines is most likely elevated in this patient? 

Question 2 of 5

3. A researcher is studying a cytokine known for its role in promoting the differentiation of T cells into Th1 cells, which are essential for cell-mediated immunity. This cytokine is also involved in activating macrophages and enhancing the microbicidal activity of these cells. Which of the following cytokines is the researcher most likely studying? 

Question 3 of 5

4. During an infection, a type of cytokine is produced by T helper cells and plays a crucial role in class-switching of B cells to produce IgE. This cytokine is particularly important in the defense against parasitic infections and in the pathogenesis of allergic diseases. Which of the following cytokines fulfills this role? 

Question 4 of 5

5. A 40-year-old man is diagnosed with a chronic infection characterized by the presence of granulomas. A key cytokine involved in the formation and maintenance of granulomas acts by inhibiting macrophage migration and promoting the transformation of macrophages into epithelioid cells and multinucleated giant cells. Which of the following cytokines is most likely involved in the formation of these granulomas? 

Question 5 of 5


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