Immunology Quiz #20: Blood transfusion reactions

1. A 45-year-old man with a history of chronic anemia secondary to kidney disease receives a red blood cell transfusion. Within minutes of initiating the transfusion, he develops fever, chills, and back pain. Laboratory findings show hemoglobinuria. Which of the following is the most likely cause of this patient's symptoms? 

Question 1 of 5

2. A 32-year-old woman develops urticaria and pruritus 10 minutes after starting a plasma transfusion. There is no fever, hypotension, or respiratory distress. Which of the following is the most likely explanation for her symptoms? 

Question 2 of 5

3. A 60-year-old man develops fever, hypotension, and dyspnea 2 hours after receiving a transfusion of packed red blood cells. Chest X-ray reveals bilateral pulmonary infiltrates. Which of the following is the most likely diagnosis? 

Question 3 of 5

4. A 27-year-old woman develops a fever and mild jaundice one week after receiving a blood transfusion. Laboratory tests reveal an increase in indirect bilirubin and a slight decrease in hemoglobin levels. No hemoglobinuria is present. Which of the following is the most likely cause of her symptoms? 

Question 4 of 5

5. Following a blood transfusion, a patient develops high fever, muscle stiffness, and an elevated heart rate. Blood tests reveal a marked increase in serum creatinine kinase. Which of the following transfusion reactions is the patient most likely experiencing? 

Question 5 of 5


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