Immunology Quiz #22: Immunodeficiency syndrome

1. A 6-month-old boy is brought to the clinic due to recurrent otitis media and oral candidiasis. His mother mentions he has had multiple respiratory infections since birth. Laboratory tests reveal decreased serum immunoglobulin levels of all classes. Which of the following is the most likely diagnosis? 

Question 1 of 5

2. A 3-year-old girl presents with a history of severe, recurrent pyogenic infections and failure to thrive. A nitroblue tetrazolium test shows no color change. Which of the following immunodeficiency syndromes is she most likely suffering from? 

Question 2 of 5

3. A 2-year-old boy is evaluated for recurrent viral, bacterial, and fungal infections since infancy. He also has chronic diarrhea and failure to thrive. Flow cytometry reveals markedly decreased T-cell receptor excision circles (TRECs). Which of the following is the most likely diagnosis? 

Question 3 of 5

4. A 24-year-old woman presents with a history of sinus and lung infections. She mentions that she has had diarrhea and malabsorption issues since childhood. Laboratory tests reveal normal T-cell counts, but significantly reduced IgA levels. Which of the following conditions is most consistent with her presentation? 

Question 4 of 5

5. An 18-year-old male with a history of eczema and recurrent skin and pulmonary infections is found to have elevated IgE levels and eosinophilia. Which of the following is the most likely diagnosis? 

Question 5 of 5


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