Immunology Quiz #23: Transplant Rejection

1. A 25-year-old male patient received an allogeneic hematopoietic stem cell transplant (HSCT) for the treatment of acute myeloid leukemia. Four weeks after the transplant, he develops a rash, diarrhea, and abnormal liver function tests. Which of the following is the most likely diagnosis? 

Question 1 of 5

2. A patient underwent a bone marrow transplant 6 months ago. He now presents with dry eyes, dry mouth, and a sclerodermatous skin rash. Pulmonary function tests reveal restrictive lung disease. Which of the following is the most likely diagnosis? 

Question 2 of 5

3. A patient who received a hematopoietic stem cell transplant develops fever, hypotension, and respiratory distress within hours after the procedure. Laboratory tests show widespread activation of the coagulation cascade. Which of the following is the most likely cause of these symptoms? 

Question 3 of 5

4. Six months after receiving an allogeneic hematopoietic stem cell transplant, a patient presents with progressive shortness of breath and a nonproductive cough. High-resolution CT of the chest reveals bilateral interstitial infiltrates. Pulmonary function tests show a restrictive pattern with reduced diffusion capacity. Which of the following is the most likely diagnosis? 

Question 4 of 5

5. Following an allogeneic bone marrow transplant, a patient develops severe abdominal pain, bloody diarrhea, and a rapidly spreading maculopapular rash. Which of the following cell types is primarily responsible for this condition? 

Question 5 of 5


 

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