Immunology Quiz #9: Differentiation of B cells

1. A 22-year-old male presents with recurrent bacterial infections. Laboratory findings indicate an inability to produce specific antibodies following vaccination. This patient's condition most likely involves a defect in the differentiation process of which of the following types of cells? 

Question 1 of 5

2. During a study session, medical students discuss the importance of T cell help in the immune response. They learn that interaction with a specific type of T cell is necessary for B cells to undergo class switching and affinity maturation. Which of the following T cells is most directly involved in this process? 

Question 2 of 5

3. A researcher is studying a group of patients with an inherited condition characterized by high levels of IgM and low levels of other antibody isotypes. This condition most likely results from a defect in which of the following processes? 

Question 3 of 5

4. A 30-year-old woman is diagnosed with a condition that results in a selective deficiency of IgA. This condition is associated with an increased frequency of mucosal infections. The deficiency in IgA production is most likely due to an impairment in the differentiation of B cells into which of the following? 

Question 4 of 5

5. In an experiment, a scientist observes that following antigen stimulation, some B cells undergo a process that results in the production of antibodies with increased affinity for the antigen. This process is known as: 

Question 5 of 5


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