Integumentary system Quiz #16, Skin Cancer  

1. A 65-year-old man with a history of extensive sun exposure presents with a new, non-healing ulcer on his nose that has been gradually enlarging over the past year. Physical examination reveals a pearly, telangiectatic nodule with a central ulceration. Biopsy of the lesion is most likely to show which of the following? 

Question 1 of 5

2. A 75-year-old woman presents with a scaly, erythematous lesion on the back of her hand that has not healed for several months. The lesion is approximately 2 cm in diameter and slightly raised. Which of the following risk factors is most strongly associated with the development of this type of skin cancer? 

Question 2 of 5

3. A 50-year-old man presents with a rapidly growing, darkly pigmented lesion on his back. Dermoscopic examination reveals irregular borders, multiple colors, and a diameter greater than 6 mm. A biopsy is performed, and pathology reveals an invasive melanoma with a Breslow depth of 4.5 mm. Which of the following is the most important prognostic factor in this patient? 

Question 3 of 5

4. A 38-year-old immunocompromised patient presents with a rapidly enlarging, shiny, red nodule on the leg. Biopsy of the lesion shows densely packed, monotonous cells with scant cytoplasm and high mitotic activity. Which of the following skin cancers is most likely in this patient? 

Question 4 of 5

5. A 60-year-old man with a history of actinic keratosis presents with a 1 cm firm, red papule on his lower lip that has been slowly growing over the past 6 months. He has a history of smoking and extensive sun exposure. A biopsy of the lesion is performed. Which of the following is the most likely diagnosis? 

Question 5 of 5


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