Microbiology Quiz #57, Antifungal Therapy  

1. A 45-year-old male with a history of HIV presents with severe pneumonia. A bronchoalveolar lavage is performed, revealing Pneumocystis jirovecii. Which of the following drugs is most appropriate for treatment and targets fungal nucleic acid synthesis? 

Question 1 of 5

2. Which of the following antifungal agents works by inhibiting the synthesis of β-(1,3)-D-glucan, an essential component of the fungal cell wall? 

Question 2 of 5

3. A patient with invasive aspergillosis requires an antifungal medication. Which of the following drugs targets the fungal cell membrane by binding ergosterol? 

Question 3 of 5

4. Which of the following antifungal agents inhibits lanosterol 14-α-demethylase, an enzyme involved in ergosterol synthesis? 

Question 4 of 5

5. A patient is diagnosed with onychomycosis due to Trichophyton rubrum. Which of the following drugs is most appropriate for treatment and specifically inhibits squalene epoxidase, thereby blocking ergosterol synthesis? 

Question 5 of 5


 

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