MICROTUBULE-EHLERS-DANLOS SYNDROME QUIZ #9

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Question 1 of 14

1. Which of the following drugs specifically targets microtubules and inhibits their polymerization, thereby disrupting mitotic spindle formation?

Question 1 of 14

Question 2 of 14

2. Primary ciliary dyskinesia (PCD) is a genetic disorder affecting the structure and function of cilia. Which of the following components is most likely to be affected in this condition?

Question 2 of 14

Question 3 of 14

3. The sodium-potassium pump is an important cell membrane protein that functions to:

Question 3 of 14

Question 4 of 14

4. Collagen is the most abundant protein in the human body and has a unique triple helix structure. Which of the following amino acids is most critical for the formation of this structure?

Question 4 of 14

Question 5 of 14

5. The hydroxylation of proline and lysine residues during collagen synthesis is dependent on which of the following cofactors?

Question 5 of 14

Question 6 of 14

6. Osteogenesis imperfecta (OI) is a genetic disorder characterized by brittle bones. Which type of collagen is most commonly affected in this condition?

Question 6 of 14

Question 7 of 14

7. Ehlers-Danlos syndrome (EDS) is a group of connective tissue disorders. Which of the following features is most characteristic of EDS?

Question 7 of 14

Question 8 of 14

8. During cell division, microtubules organize into a structure known as the mitotic spindle. What is the primary role of the mitotic spindle?

Question 8 of 14

Question 9 of 14

9. Which of the following best describes the arrangement of microtubules within most motile cilia?

Question 9 of 14

Question 10 of 14

10. How does the sodium-potassium pump contribute to the maintenance of the resting membrane potential in neurons?

Question 10 of 14

Question 11 of 14

11. In addition to being a major component of bone, where else in the body is type I collagen prominently found?

Question 11 of 14

Question 12 of 14

12. What is the initial form of collagen synthesized by fibroblasts called, and where does it typically occur?

Question 12 of 14

Question 13 of 14

13. What is a common non-skeletal symptom associated with osteogenesis imperfecta?

Question 13 of 14

Question 14 of 14

14. For diagnostic purposes, which of the following tests might be used to investigate a suspected case of Ehlers-Danlos syndrome?

Question 14 of 14


 

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