MSK Quiz#14, Vascular Smooth Muscle Physiology  

1. A 65-year-old man with a history of hypertension is prescribed a new medication that acts by opening potassium channels in vascular smooth muscle cells. What is the primary effect of opening these channels on vascular smooth muscle tone? 

Question 1 of 5

2. During a clinical trial for a novel antihypertensive drug, researchers find that the drug inhibits phospholipase C (PLC) activity in vascular smooth muscle cells. Which of the following downstream effects is most likely reduced by this drug? 

Question 2 of 5

3. A researcher is studying the effects of nitric oxide (NO) on vascular smooth muscle cells. She observes that NO leads to vasodilation. This effect is primarily mediated through which of the following mechanisms? 

Question 3 of 5

4. A patient is given a medication that mimics the action of endothelin-1 (ET-1) on vascular smooth muscle. Which of the following effects on blood vessels is most likely to occur as a result of this medication? 

Question 4 of 5

5. A group of researchers is investigating a new drug that blocks voltage-gated calcium channels in vascular smooth muscle. Which of the following is the most likely immediate effect of this drug on the vascular system? 

Question 5 of 5


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