MSK Quiz#21, Osteoporosis and Osteoarthritis  

1. A 68-year-old postmenopausal woman presents with a history of lower back pain and a recent minimal trauma vertebral compression fracture. Her bone density test shows a T-score of -2.8. Which of the following best describes the underlying pathophysiology of her condition? 

Question 1 of 5

2. A 55-year-old male with a history of knee pain exacerbated by activity and relieved by rest presents for evaluation. Physical examination reveals crepitus and joint tenderness, but no signs of inflammation. Which of the following is the most likely diagnosis? 

Question 2 of 5

3. A 60-year-old female has been diagnosed with osteoporosis. In addition to calcium and vitamin D supplementation, which of the following pharmacological treatments is primarily aimed at inhibiting osteoclast-mediated bone resorption? 

Question 3 of 5

4. Which of the following risk factors is associated with the development of osteoarthritis? 

Question 4 of 5

5. A postmenopausal 72-year-old woman is evaluated for a history of multiple fractures following minor falls. Laboratory tests reveal normal serum calcium, phosphorus, and alkaline phosphatase levels. A bone mineral density test shows a T-score of -3.0 at the lumbar spine. Which of the following is the most appropriate first-line therapy? 

Question 5 of 5


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