MSK Quiz#32, Polymyositis and Dermatomyositis  

1. A 50-year-old female presents with a 6-month history of progressive muscle weakness, difficulty climbing stairs and rising from a seated position. She also reports a rash on her face and hands. Physical examination reveals heliotrope rash and Gottron's papules. Laboratory findings show elevated serum creatine kinase (CK) levels. Which of the following is the most likely diagnosis? 

Question 1 of 5

2. A 45-year-old man with a recent diagnosis of polymyositis starts treatment with high-dose corticosteroids. Despite initial improvement, he experiences a relapse of symptoms. Which of the following is the most appropriate next step in management? 

Question 2 of 5

3. A 55-year-old woman with dermatomyositis is found to have interstitial lung disease (ILD) on high-resolution CT scan. Which of the following antibodies is most likely to be present in this patient? 

Question 3 of 5

4. In patients diagnosed with dermatomyositis, which of the following malignancies should be most aggressively screened for? 

Question 4 of 5

5. A 60-year-old male with a history of polymyositis presents with dysphagia and weight loss. Which of the following complications is most likely responsible for these symptoms? 

Question 5 of 5


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