Neurology Quiz #15: Basal Ganglia Anatomy and Pathology

1. A 70-year-old man presents with a 5-year history of progressive bradykinesia, rigidity, and rest tremor. His physician explains that his symptoms are due to the degeneration of dopaminergic neurons in a specific part of the brain. Which area is most directly affected in this patient's condition? 

Question 1 of 5

2. A 45-year-old woman presents with sudden, jerky, and unpredictable movements of her limbs. Genetic testing reveals an expansion of CAG repeats. Which part of the basal ganglia is most affected in this condition? 

Question 2 of 5

3. A neurology resident explains to a medical student that increased activity of the indirect pathway within the basal ganglia can lead to hypokinetic movement disorders. Which neurotransmitter is primarily responsible for inhibiting the thalamus in this pathway? 

Question 3 of 5

4. A patient presents with high-pitched cries, writhing, and twisting movements of the body. These symptoms most likely result from a decrease in inhibitory output from which of the following structures to the thalamus? 

Question 4 of 5

5. A patient undergoes neurosurgery to alleviate severe tremors. The surgical procedure involves creating a lesion in a specific part of the basal ganglia. This intervention likely targets which of the following structures to reduce the patient's symptoms? 

Question 5 of 5


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