Pathology Quiz #14: Granulomatous Inflammation

1. A 34-year-old female presents with a persistent cough, night sweats, and weight loss over the past two months. A chest X-ray reveals a cavitary lesion in the upper lobe of the right lung. Sputum smears are positive for acid-fast bacilli. Which of the following cell types is most responsible for the formation of the granuloma observed in this patient? 

Question 1 of 4

2. A 50-year-old man with a history of sarcoidosis presents with dyspnea and dry cough. A chest CT scan shows bilateral hilar lymphadenopathy and a tissue biopsy is obtained. A histopathology image of the biopsy specimen is shown below. Which of the following cytokines is most implicated in the pathophysiology of the lesion shown in the histology image? 

Question 2 of 4

3. A 28-year-old woman presents with a painful rash on her legs. Physical examination reveals tender, red nodules. An image of the skin lesions is shown below. Biopsy of a lesion shows granulomatous inflammation with neutrophils surrounding necrotic fat tissue. Which of the following is the most likely diagnosis? 

Question 3 of 4

4. A researcher is studying a new infectious agent isolated from patients with granulomatous inflammation of the lymph nodes. When macrophages are exposed to this agent in vitro, they secrete large amounts of IL-12. Which of the following immune responses is most likely enhanced by IL-12 in this context? 

Question 4 of 4


¡Por tiempo limitado!

Unete a nuestro boletín mensual y obtén todos nuestros talleres USMLE/ECFMG ¡GRATIS! (+100 videos)

¡Únete a nuestra comunidad de IMGs!

¡Obtén actualizaciones mensuales USMLE y ECFMG, además, obtén un taller USMLE gratis al instante!

"Taller 01: ¿Qué es el USMLE?”

Taller Gratuito USMLE

Este taller proporciona un análisis en profundidad de todos los exámenes USMLE, consejos para tomar exámenes y cómo estudiar de manera efectiva.


Especialista ECFMG: Dr. Carla Rebeca Lainez Casal

Facultad de Medicina: Universidad Catholica de Santiago de Guayaquil
ECFMG Certification date: October 13, 2022.
Residency: 2023 Internal Medicine Applicant
+1 7542724970