Pathology Quiz #24: Immune Stains in Pathology

1. A 45-year-old woman presents with a solitary, firm mass in the upper outer quadrant of her right breast. A biopsy is performed, and histological examination reveals invasive ductal carcinoma. Immunohistochemical staining is likely to be positive for which of the following markers to support the diagnosis? 

Question 1 of 4

2. A 60-year-old man with a history of smoking presents with a cough and unintentional weight loss. A chest CT scan reveals a mass in the right lung, and a biopsy is obtained. Histopathological examination is suggestive of small cell lung carcinoma (SCLC). Which of the following immunohistochemical stains is most likely to be positive in this tumor? 

Question 2 of 4

3. A 3-year-old boy is brought to the pediatrician because his parents noticed an abdominal mass. Imaging studies reveal a solid tumor of the adrenal gland. Biopsy and subsequent immunohistochemical staining of the tumor are most likely to show positivity for which of the following markers, supporting the diagnosis? 

Question 3 of 4

4. A 35-year-old woman presents with a rapidly enlarging mass on her thigh. A biopsy of the mass is performed, and histopathological examination suggests a diagnosis of malignant melanoma. Which of the following immunohistochemical stains is most likely to be positive in this tumor? 

Question 4 of 4


 

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