Pathology Quiz #6: Ionizing Radiation Toxicity

1. A 30-year-old male undergoes radiation therapy for testicular cancer. Several weeks into treatment, he develops acute skin erythema and dry desquamation in the irradiated area. Which of the following best explains the mechanism of injury seen in this patient’s skin? 

Question 1 of 5

2. A 55-year-old female with a history of left breast cancer treated with radiation therapy presents with symptoms of dysphagia and odynophagia. Endoscopy reveals mucosal inflammation and ulceration in the esophagus. Which of the following cell types is most susceptible to the ionizing radiation that led to her condition? 

Question 2 of 5

3. A worker at a nuclear facility is accidentally exposed to a high dose of ionizing radiation. He is at increased risk of developing which of the following conditions in the long term? 

Question 3 of 5

4. During a lecture on radiation toxicity, a professor explains that ionizing radiation can generate free radicals within cells. Which of the following molecules is primarily responsible for the formation of these free radicals when irradiated? 

Question 4 of 5

5. A 45-year-old oncologist regularly works with radiation therapy in treating cancer patients. Despite using protective measures, there is concern about long-term exposure to low levels of ionizing radiation. Which of the following is the most likely long-term effect of such exposure? 

Question 5 of 5


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