Pathology Quiz #9: Inflammation

1. A 25-year-old woman presents to the clinic with redness, warmth, and swelling in her left lower leg. She reports that she started feeling these symptoms a day after accidentally cutting her leg on a rusty nail. Which of the following inflammatory mediators is primarily responsible for the redness and warmth (erythema and hyperthermia) observed in this patient's affected leg? 

Question 1 of 5

2. A research team is studying the early stages of inflammation in response to bacterial infection. They note that neutrophils are the first leukocytes to arrive at the site of infection. Which of the following chemotactic agents is most likely responsible for the early recruitment of neutrophils in an acute inflammatory response? 

Question 2 of 5

3. A 50-year-old male with chronic arthritis is taking a nonsteroidal anti-inflammatory drug (NSAID) to manage his symptoms. NSAIDs alleviate pain and inflammation primarily by inhibiting the synthesis of which of the following substances? 

Question 3 of 5

4. Following tissue injury, mast cells degranulate and release histamine. Which of the following best describes the immediate effect of histamine release on the vasculature? 

Question 4 of 5

5. A laboratory technician accidentally cuts their finger on a glass slide. Within minutes, the wound becomes red and slightly swollen. This initial phase of inflammation is primarily mediated by the release of which substance from injured cells? 

Question 5 of 5


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