Pharmacology Quiz #2: Pharmacokinetics

1. A 55-year-old man with chronic kidney disease is prescribed a medication that is known to be eliminated exclusively by renal excretion. Which pharmacokinetic parameter is most directly affected by this patient's condition? 

Question 1 of 5

2. A new antihypertensive drug shows a high affinity for its target receptor and requires only a low concentration to achieve 50% of its maximum effect. Which of the following pharmacodynamic properties best describes this drug? 

Question 2 of 5

3. A patient is prescribed a medication that follows first-order kinetics, meaning that a constant proportion of the drug is eliminated per unit time. Which of the following best describes the effect of doubling the dose of this medication? 

Question 3 of 5

4. A drug used to treat anxiety has a narrow therapeutic index. Which of the following best explains the implication of this characteristic? 

Question 4 of 5

5. A medication is noted to have extensive binding to plasma proteins. What is the potential consequence of this characteristic when another drug with a higher affinity for the same plasma proteins is administered concurrently? 

Question 5 of 5


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