Pharmacology Quiz #20: Phosphodiesterase Inhibitors

1. A 45-year-old man with a history of chronic obstructive pulmonary disease (COPD) is prescribed a new medication to improve his respiratory symptoms. This medication works by inhibiting an enzyme that degrades cyclic AMP, leading to bronchodilation. Which of the following is the most likely mechanism of action of this drug? 

Question 1 of 5

2. A 60-year-old female with pulmonary hypertension is started on a medication that reduces pulmonary vascular resistance and improves symptoms of dyspnea on exertion. This medication likely exerts its therapeutic effect by: 

Question 2 of 5

3. A research team is studying a new drug for the treatment of heart failure. This drug is found to increase myocardial contractility and decrease symptoms of fatigue and shortness of breath in affected patients. The drug's mechanism of action is most likely related to: 

Question 3 of 5

4. A man is prescribed a medication for erectile dysfunction. This medication enhances the effect of nitric oxide by inhibiting the degradation of a specific cyclic nucleotide in penile smooth muscle, leading to vasodilation and erection. This drug is most likely: 

Question 4 of 5

5. A pediatric patient with a severe form of congenital heart disease is treated with a medication post-surgery to manage pulmonary hypertension and facilitate recovery. This medication works by inhibiting a specific enzyme, leading to vasodilation of the pulmonary vasculature. The medication used is most likely: 

Question 5 of 5


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