Pharmacology Quiz #26: Cytochrome P-450 Interactions

1. A 45-year-old man is brought to the emergency department after developing a widespread, blistering rash and fever two weeks following the initiation of a medication for a urinary tract infection. His medical history is notable for HIV. Examination reveals confluent erythematous plaques over his trunk, face, and oral mucosa. Which of the following medications most likely contributed to this patient's condition? 

Question 1 of 5

2. A 32-year-old woman with a history of systemic lupus erythematosus (SLE) develops a high fever, sore throat, and malaise after starting a new medication for a urinary tract infection. Laboratory findings show leukopenia and elevated liver enzymes. Which of the following medications is most likely responsible for her symptoms?

Question 2 of 5

3. A 58-year-old man with type 2 diabetes mellitus is prescribed a medication to improve glycemic control. He returns to the clinic complaining of dizziness, headache, and confusion. His blood glucose level is found to be 55 mg/dL. Which of the following medications is most likely responsible for his symptoms?

Question 3 of 5

4. A 60-year-old man with hypertension and chronic kidney disease is started on a diuretic. One week later, he presents with increased serum creatinine and decreased urine output. Which of the following medications is most likely responsible for the deterioration in renal function? 

Question 4 of 5

5. A 27-year-old woman with no significant medical history develops a sudden onset of symmetrical joint pain, particularly in her wrists and knees, after starting a medication for rheumatoid arthritis. She also reports experiencing photosensitivity. Which of the following medications most likely caused her symptoms?

Question 5 of 5


 

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