Renal Quiz #15 Nephritic and Nephrotic Syndromes

1. A 9-year-old boy presents with periorbital edema and cola-colored urine following a recent upper respiratory tract infection. His blood pressure is elevated. Laboratory findings reveal hematuria, proteinuria less than 2 g/day, and low serum complement levels. Which of the following is the most likely diagnosis? 

Question 1 of 5

2. A 35-year-old woman presents with 4 days of generalized edema and foamy urine. Laboratory tests reveal proteinuria exceeding 5 grams per day, hypoalbuminemia, and hyperlipidemia. There are no cells or casts seen on urinary sediment examination. Which of the following is the most likely diagnosis? 

Question 2 of 5

3. A 20-year-old man with a history of heroin abuse presents with hematuria, hypertension, and mild proteinuria. A renal biopsy shows focal segmental glomerulosclerosis (FSGS). Which of the following is the most likely underlying mechanism for this patient's renal pathology? 

Question 3 of 5

4. A 50-year-old man with a history of hepatitis B infection presents with fatigue, weight loss, and dark urine. Laboratory findings show elevated creatinine, hematuria, and proteinuria. A renal biopsy reveals subendothelial immune complex deposits and "spike and dome" appearances on electron microscopy. Which of the following is the most likely diagnosis? 

Question 4 of 5

5. A 30-year-old woman presents with malaise, facial puffiness, and decreased urine output. She has a history of systemic lupus erythematosus (SLE). A renal biopsy shows wire loop lesions with immune deposits. Which of the following is the most likely diagnosis? 

Question 5 of 5


 

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