Renal Quiz #20Acute Kidney Injury and Interstitial Nephritis

1. A 28-year-old man presents to the emergency department with generalized fatigue, reduced urine output, and flank pain. He recently started taking antibiotics for a skin infection. Laboratory findings reveal elevated blood urea nitrogen (BUN) and creatinine, with urinalysis showing white blood cell casts. Which of the following antibiotics is most likely responsible for his condition? 

Question 1 of 5

2. A 65-year-old woman with chronic hypertension is admitted with confusion and lethargy. Her medications include lisinopril, hydrochlorothiazide, and ibuprofen for chronic knee pain. Laboratory results show serum creatinine has increased from 1.2 mg/dL (baseline) to 2.6 mg/dL. Urinalysis is normal. Which of the following is the most likely cause of acute kidney injury in this patient? 

Question 2 of 5

3. A 55-year-old man is admitted with rash, fever, and acute kidney injury. He started taking a new medication for gout 2 weeks ago. Laboratory findings include elevated serum creatinine, eosinophilia, and eosinophiluria. Which of the following medications is most likely responsible for his condition? 

Question 3 of 5

4. A 72-year-old man with a history of chronic kidney disease presents with a 2-day history of anuria. He has been taking over-the-counter pain relievers for back pain. Physical examination reveals mild flank tenderness. Laboratory tests show significantly elevated blood urea nitrogen and creatinine levels. Which of the following over-the-counter medications is most likely responsible for his acute kidney injury? 

Question 4 of 5

5. A patient presents with generalized edema, oliguria, and new-onset hypertension. He has a history of recent upper respiratory tract infection. Laboratory tests reveal elevated serum creatinine, low serum C3 levels, and normal serum C4 levels. Urinalysis shows hematuria, proteinuria, and red blood cell casts. Which of the following is the most likely diagnosis? 

Question 5 of 5


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