Reproductive Quiz #30, Cervical and Vulvar Pathology  

1. A 52-year-old woman presents with postmenopausal bleeding. Colposcopy reveals a lesion on the cervix, and biopsy confirms squamous cell carcinoma. Which of the following human papillomavirus (HPV) types is most likely associated with this malignancy?

Question 1 of 5

2. A 35-year-old woman has been diagnosed with cervical intraepithelial neoplasia grade 2 (CIN 2) after a Pap smear and subsequent biopsy. Which of the following best describes the pathophysiology of this condition?

Question 2 of 5

3. A 60-year-old woman presents with a vulvar lesion. Biopsy reveals a malignant tumor composed of large cells with abundant pale cytoplasm and central nuclei. The tumor is positive for periodic acid-Schiff (PAS) stain. Which of the following is the most likely diagnosis?

Question 3 of 5

4. A 45-year-old woman presents with a painful vulvar lesion. Biopsy shows a well-differentiated squamous cell carcinoma with evidence of human papillomavirus (HPV) integration. Which of the following HPV vaccine types would most likely have provided protection against the HPV subtype causing her cancer?

Question 4 of 5

5. A 28-year-old woman presents with a white, lacy pattern on the vulva that has been causing itchiness. Biopsy reveals hyperkeratosis and a band-like lymphocytic infiltrate below the squamous epithelium. Which of the following is the most likely diagnosis?

Question 5 of 5


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