Respiratory Quiz #21, Restrictive Lung Disease  

1. A 55-year-old female with a 20-year history of rheumatoid arthritis presents with progressive dyspnea on exertion and a nonproductive cough. High-resolution CT of the chest reveals bibasilar reticular opacities with minimal honeycombing. Pulmonary function tests show a reduced total lung capacity (TLC) and a normal FEV1/FVC ratio. Which of the following is the most likely diagnosis? 

Question 1 of 5

2. A 33-year-old male presents with shortness of breath, dry cough, and bilateral hilar lymphadenopathy on chest X-ray. Serum angiotensin-converting enzyme (ACE) levels are elevated. Lung biopsy shows noncaseating granulomas. Pulmonary function tests demonstrate a reduced diffusing capacity for carbon monoxide (DLCO) and normal spirometry. Which of the following is the most likely diagnosis?

Question 2 of 5

3. A 60-year-old female, who was previously a shipyard worker, presents with dyspnea on exertion and clubbing. Chest X-ray shows pleural plaques, and high-resolution CT reveals interstitial fibrosis with a subpleural and basal predominance. Which of the following exposures is most likely responsible for her condition? 

Question 3 of 5

4. A 45-year-old male with no significant past medical history presents with progressive dyspnea over several months. High-resolution CT of the chest shows diffuse ground-glass opacities with traction bronchiectasis. Pulmonary function tests reveal a restrictive pattern with a markedly reduced DLCO. An autoantibody panel is negative. Which of the following is the most likely diagnosis? 

Question 4 of 5

5. A 28-year-old male presents with dyspnea, cough, and fever. He works as a farmer and has been exposed to moldy hay. Chest imaging shows patchy infiltrates, and pulmonary function tests indicate a restrictive lung disease. Which of the following is the most likely diagnosis? 

Question 5 of 5


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